SLC45A2

Across TCGA cell cohorts, SLC45A2 mutation is significantly associated with the RNA expression of many other genes, with 68 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible SLC45A2-associated genes across cancer lineages are C4BPA, C6orf118, and OR2T29. Each is linked with SLC45A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC45A2-to-partner and partner-to-SLC45A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C4BPA grouped by SLC45A2-low versus SLC45A2-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC45A2→partner) and Y-score (partner→SLC45A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	C4BPA →	+0.023	+3.376	<.001	.002	3	2
LARGE_INTESTINE	C6orf118 →	+0.141	+3.600	<.001	<.001	3	2
OESOPHAGUS	OR2T29 →	+0.116	+4.906	<.001	.006	3	1
OESOPHAGUS	TSPY8 →	+0.033	+4.906	<.001	.006	3	1
SKIN	C20orf203 →	+0.023	+3.297	.002	.002	3	1
SKIN	TMEM235 →	+0.006	+3.217	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 68 associations by consensus.

C4BPA by SLC45A2 expression — SKIN

Explore this box plot interactively →