SLC45A1

Across TCGA cell cohorts, SLC45A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,538 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SLC45A1-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Positive regulation of lamellipodium assembly, and Negative regulation of myoblast fusion. Each is linked with SLC45A1 in more than 8 cancer types. Because this analysis shows association rather than direction, both SLC45A1-to-partner and partner-to-SLC45A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by SLC45A1-low versus SLC45A1-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC45A1→partner) and Y-score (partner→SLC45A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Negative regulation of syncytium formation by plasma membrane fusion →	+0.074	+0.741	<.001	.001	3	9
LUNG_SCLC	Positive regulation of lamellipodium assembly →	+0.087	+0.711	<.001	.002	3	9
LARGE_INTESTINE	Negative regulation of myoblast fusion →	+0.085	+0.455	<.001	.006	2	9
CNS	Negative regulation of cell cycle G1/S phase transition →	+0.053	+0.514	.001	.004	3	8
SKIN	Regulation of intracellular transport →	+0.060	+0.617	<.001	<.001	3	8
LARGE_INTESTINE	Response to UV →	+0.040	+0.477	<.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,538 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by SLC45A1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →