SLC45A1

Across TCGA cell cohorts, SLC45A1 mutation is significantly associated with the RNA expression of many other genes, with 604 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC45A1-associated genes across cancer lineages are SSX7, ACSM4, and OR56A4. Each is linked with SLC45A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC45A1-to-partner and partner-to-SLC45A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SSX7 grouped by SLC45A1-low versus SLC45A1-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC45A1→partner) and Y-score (partner→SLC45A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	SSX7 →	+0.017	+4.369	<.001	.008	3	2
BLOOD_Leukemia	ACSM4 →	+0.058	+4.234	<.001	.003	3	2
SKIN	OR56A4 →	+0.014	+3.632	<.001	.003	3	2
OESOPHAGUS	KRTAP10-7 →	+0.006	+4.906	<.001	.006	3	1
SOFT_TISSUE	TGIF2LX →	+0.807	+4.882	<.001	.001	3	1
SOFT_TISSUE	DEFB4B →	+0.090	+4.977	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 604 associations by consensus.

SSX7 by SLC45A1 expression — SOFT_TISSUE

Explore this box plot interactively →