SLC44A3

Across TCGA patient cohorts, SLC44A3 mutation is significantly associated with the RNA expression of many other genes, with 3,373 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC44A3-associated genes across cancer lineages are MIR4310, CACNA2D1, and RN7SL100P. Each is linked with SLC44A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC44A3-to-partner and partner-to-SLC44A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4310 grouped by SLC44A3-low versus SLC44A3-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC44A3→partner) and Y-score (partner→SLC44A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	MIR4310 →	+0.481	+5.226	<.001	.003	3	2
UCEC	CACNA2D1 →	+0.557	+2.310	<.001	.005	3	2
SKCM	RN7SL100P →	+0.096	+3.362	<.001	.006	3	2
UCEC	GPR75-ASB3 →	+0.066	+1.957	<.001	.005	3	2
COAD	RPL23AP90 →	+0.366	+3.522	.006	.007	3	2
UCEC	RNA5SP455 →	+0.185	+3.662	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,373 associations by consensus.

MIR4310 by SLC44A3 expression — STAD

Explore this box plot interactively →