SLC44A3

Across TCGA patient cohorts, SLC44A3 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC44A3-associated genes across cancer lineages are ASNS, JNK_pT183_Y185, and MEK1. Each is linked with SLC44A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC44A3-to-partner and partner-to-SLC44A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by SLC44A3-low versus SLC44A3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC44A3→partner) and Y-score (partner→SLC44A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.437	+1.906	.002	.016	3	2
UCEC	JNK_pT183_Y185 →	-0.180	-3.459	.007	.005	3	1
UCEC	MEK1 →	+0.400	+2.415	.006	.003	3	1
UCEC	mTOR_pS2448 →	-0.206	-3.565	<.001	.002	3	1
UCEC	Notch1 →	+0.143	+2.331	.011	.019	3	1
UCEC	p38-MAPK_pT180_Y182 →	-0.574	-3.169	.001	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

ASNS by SLC44A3 expression — UCEC

Explore this box plot interactively →