SLC44A3

Across TCGA cell cohorts, SLC44A3 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC44A3-associated genes across cancer lineages are TBC1D21, OR52H1, and BTNL2. Each is linked with SLC44A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC44A3-to-partner and partner-to-SLC44A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TBC1D21 grouped by SLC44A3-low versus SLC44A3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC44A3→partner) and Y-score (partner→SLC44A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TBC1D21 →	+0.012	+4.437	<.001	.004	3	1
LARGE_INTESTINE	OR52H1 →	+0.031	+4.347	<.001	.001	3	1
STOMACH	BTNL2 →	+0.122	+4.129	<.001	.007	3	1
OVARY	OR10A5 →	+0.025	+4.029	.001	.009	3	1
LUNG_NSCLC_LUAD	ADAM2 →	+0.072	+3.734	<.001	.006	3	1
LUNG_NSCLC_LUAD	H2BC1 →	+0.643	+3.544	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

TBC1D21 by SLC44A3 expression — LARGE_INTESTINE

Explore this box plot interactively →