SLC44A3

mutation — cross-omics
Cross-omicsMUTATION → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SLC44A3 mutation is significantly associated with the mutation status of many other genes, with 1,907 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible SLC44A3-associated genes across cancer lineages are CNN2, COL6A2, and TRPM5. Each is linked with SLC44A3 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC44A3-to-partner and partner-to-SLC44A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CNN2 grouped by SLC44A3-low versus SLC44A3-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC44A3→partner) and Y-score (partner→SLC44A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHCNN2 →+4.285+3.357.005.00514
BONECOL6A2 →+5.437+5.437.003.00313
BONETRPM5 →+5.437+5.437.003.00313
CNSMAML3 →+5.277+4.459.005.00513
LUNG_NSCLC_LUADGRIN2D →+3.584+4.063.003.00313
LUNG_NSCLC_LUADWNT5A →+5.000+4.187.008.00813
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,907 associations by consensus.

CNN2 by SLC44A3 expression — STOMACH

Box plot of CNN2 in SLC44A3-low vs SLC44A3-high samples in STOMACH.

Explore this box plot interactively →

Exploration