SLC44A2

Across TCGA patient cohorts, SLC44A2 mutation is significantly associated with the RNA expression of many other genes, with 3,492 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC44A2-associated genes across cancer lineages are RNU4-14P, PYGB, and CENPT. Each is linked with SLC44A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC44A2-to-partner and partner-to-SLC44A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU4-14P grouped by SLC44A2-low versus SLC44A2-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC44A2→partner) and Y-score (partner→SLC44A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU4-14P →	+0.469	+4.084	<.001	.005	3	3
UCEC	PYGB →	+0.418	+1.805	.001	.007	3	2
UCEC	CENPT →	+0.282	+2.055	.007	.005	3	2
UCEC	CORO2B →	-0.506	-2.662	.004	<.001	3	2
UCEC	BLOC1S6 →	+0.399	+1.923	.004	.009	3	2
UCEC	GPI →	+0.537	+1.847	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,492 associations by consensus.

RNU4-14P by SLC44A2 expression — HNSC

Explore this box plot interactively →