SLC44A2

Across TCGA cell cohorts, SLC44A2 mutation is significantly associated with the RNA expression of many other genes, with 304 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC44A2-associated genes across cancer lineages are ACTL7A, BHLHE23, and BTBD16. Each is linked with SLC44A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC44A2-to-partner and partner-to-SLC44A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACTL7A grouped by SLC44A2-low versus SLC44A2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC44A2→partner) and Y-score (partner→SLC44A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ACTL7A →	+0.019	+2.353	<.001	.008	3	2
BLOOD_Leukemia	BHLHE23 →	+1.095	+3.691	.002	.005	3	1
BLOOD_Leukemia	BTBD16 →	+0.077	+3.959	<.001	.005	3	1
BLOOD_Leukemia	ASZ1 →	+0.090	+3.567	.003	.003	3	1
BLOOD_Leukemia	DIRAS2 →	+0.115	+4.502	<.001	.001	3	1
BLOOD_Leukemia	OR10T2 →	+0.608	+3.691	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 304 associations by consensus.

ACTL7A by SLC44A2 expression — LARGE_INTESTINE

Explore this box plot interactively →