SLC44A1

Across TCGA pan-cancer cohorts, SLC44A1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SLC44A1 data layer compared with 28 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SLC44A1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated SLC44A1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

LUAD, CCRCC, and PDAC are the cancer types where SLC44A1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	II,III,IV	0.445	0.844	.013	4	view →
CCRCC	DFS	Median	All	0.830	0.656	.013	2	view →
PDAC	OS	Quartile	All	0.607	0.388	.034	2	view →
HNSC	DFS	Quartile	II,III,IV	0.716	0.480	.048	1	view →
LSCC	DFS	Tertile	II,III,IV	0.515	1.000	.040	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

SLC44A1–LUAD (OS)

Open the LUAD breakdown →