SLC44A1

Across TCGA patient cohorts, SLC44A1 mutation is significantly associated with the total protein of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC44A1-associated genes across cancer lineages are p62 Lck ligand, Rictor_pT1135, and Caspase-7-cleavedD198. Each is linked with SLC44A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC44A1-to-partner and partner-to-SLC44A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p62 Lck ligand grouped by SLC44A1-low versus SLC44A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC44A1→partner) and Y-score (partner→SLC44A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p62 Lck ligand →	+0.339	+1.746	<.001	.003	3	2
UCEC	Rictor_pT1135 →	-0.083	-1.847	.006	.007	3	2
UCEC	Caspase-7-cleavedD198 →	+0.402	+1.378	.023	.008	3	2
UCEC	4E-BP1 →	+0.304	+2.050	<.001	<.001	3	2
UCEC	C-Raf →	+0.174	+1.807	<.001	<.001	3	2
UCEC	Cyclin-B1 →	+0.661	+1.807	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

p62 Lck ligand by SLC44A1 expression — UCEC

Explore this box plot interactively →