SLC44A1

Across TCGA cell cohorts, SLC44A1 mutation is significantly associated with the mutation status of many other genes, with 2,170 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC44A1-associated genes across cancer lineages are DCLK1, KCNH4, and ENPP7. Each is linked with SLC44A1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC44A1-to-partner and partner-to-SLC44A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DCLK1 grouped by SLC44A1-low versus SLC44A1-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC44A1→partner) and Y-score (partner→SLC44A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	DCLK1 →	+5.614	+5.044	.003	.003	1	4
CNS	KCNH4 →	+4.614	+4.614	.006	.006	1	4
SKIN	ENPP7 →	+5.053	+4.239	.007	.007	1	3
CNS	EP300 →	+3.199	+4.633	.003	.003	1	3
CNS	INTS2 →	+4.614	+4.614	.006	.006	1	3
CNS	EFTUD2 →	+4.199	+5.347	<.001	<.001	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,170 associations by consensus.

DCLK1 by SLC44A1 expression — CNS

Explore this box plot interactively →