SLC43A3

Across TCGA pan-cancer cohorts, SLC43A3 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated SLC43A3 data layer compared with 24 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher SLC43A3 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC43A3 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

CCRCC, COAD, and PDAC are the cancer types where SLC43A3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	All	0.592	1.000	.012	11	view →
COAD	DFS	Median	All	0.876	1.000	.013	6	view →
PDAC	OS	Quartile	All	0.298	0.844	.024	6	view →
HNSC	DFS	Quartile	II,III,IV	1.000	0.899	.018	6	view →
LSCC	DFS	Median	II,III,IV	0.565	0.838	.022	4	view →
UCEC	DFS	Median	All	0.814	0.934	.048	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

SLC43A3–CCRCC (DFS)

Open the CCRCC breakdown →