SLC43A3

Across TCGA cell cohorts, SLC43A3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,838 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SLC43A3-associated GO terms across cancer lineages are Guanine transport, Guanine transmembrane transport, and Purine nucleobase transmembrane transport. Each is linked with SLC43A3 in more than 13 cancer types. Because this analysis shows association rather than direction, both SLC43A3-to-partner and partner-to-SLC43A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Guanine transport grouped by SLC43A3-low versus SLC43A3-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC43A3→partner) and Y-score (partner→SLC43A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Guanine transport →	+0.293	+2.278	<.001	<.001	3	14
CNS	Guanine transmembrane transport →	+0.293	+2.278	<.001	<.001	3	14
CNS	Purine nucleobase transmembrane transport →	+0.333	+2.155	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Urokinase plasminogen activator signaling pathway →	+1.208	+4.213	.002	<.001	3	12
LIVER	Regulation of plasminogen activation →	+0.342	+4.599	<.001	<.001	3	11
LIVER	Negative regulation of small GTPase mediated signal transduction →	+0.097	+3.942	.004	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,838 associations by consensus.

Guanine transport by SLC43A3 expression — CNS

Explore this box plot interactively →