SLC43A2

Across TCGA pan-cancer cohorts, SLC43A2 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SLC43A2 data layer compared with 28 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher SLC43A2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SLC43A2 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LSCC show a favorable association.

CCRCC, LSCC, and LUAD are the cancer types where SLC43A2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	II,III,IV	0.932	0.799	.014	16	view →
LSCC	OS	Median	III,IV	0.882	0.378	.001	15	view →
LUAD	DFS	Median	II,III,IV	0.826	0.373	.011	8	view →
UCEC	DFS	Tertile	All	0.860	1.000	.017	4	view →
HNSC	DFS	Quartile	All	0.321	0.895	.031	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

SLC43A2–CCRCC (DFS)

Open the CCRCC breakdown →