SLC43A2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC43A2 mutation is significantly associated with the RNA expression of many other genes, with 1,021 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC43A2-associated genes across cancer lineages are RN7SL375P, OR1L1, and DSCR4. Each is linked with SLC43A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC43A2-to-partner and partner-to-SLC43A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL375P grouped by SLC43A2-low versus SLC43A2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC43A2→partner) and Y-score (partner→SLC43A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRN7SL375P →+0.160+3.705<.001.00833
HNSCOR1L1 →+0.045+5.008<.001.00432
CESCDSCR4 →+0.304+3.934.004.00532
CESCMTND4LP20 →+0.100+5.579<.001.00132
CESCLINC02476 →+0.644+3.934<.001.00532
CESCCBX3P6 →+0.076+4.559<.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,021 associations by consensus.

RN7SL375P by SLC43A2 expression — CESC

Box plot of RN7SL375P in SLC43A2-low vs SLC43A2-high samples in CESC.

Explore this box plot interactively →

Exploration