SLC43A2

Across TCGA patient cohorts, SLC43A2 mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC43A2-associated genes across cancer lineages are GAPDH, Cyclin-B1, and EGFR_pY1068. Each is linked with SLC43A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC43A2-to-partner and partner-to-SLC43A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GAPDH grouped by SLC43A2-low versus SLC43A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC43A2→partner) and Y-score (partner→SLC43A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GAPDH →	+0.509	+2.000	.018	.030	3	2
UCEC	Cyclin-B1 →	+0.569	+3.169	.011	.018	3	2
UCEC	EGFR_pY1068 →	-0.295	-2.321	.003	.033	3	1
UCEC	eIF4E →	+0.189	+3.459	.026	.005	3	1
UCEC	ERK2 →	+0.224	+2.459	.003	.018	3	1
UCEC	JNK2 →	+0.243	+3.331	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

GAPDH by SLC43A2 expression — UCEC

Explore this box plot interactively →