SLC43A2

Across TCGA cell cohorts, SLC43A2 mutation is significantly associated with the RNA expression of many other genes, with 51 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC43A2-associated genes across cancer lineages are TFDP3, SH3GL2, and GID4. Each is linked with SLC43A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC43A2-to-partner and partner-to-SLC43A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFDP3 grouped by SLC43A2-low versus SLC43A2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC43A2→partner) and Y-score (partner→SLC43A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TFDP3 →	+0.021	+2.518	<.001	.006	3	2
LARGE_INTESTINE	SH3GL2 →	+1.627	+3.667	<.001	<.001	3	1
LARGE_INTESTINE	GID4 →	+0.791	+3.067	<.001	.009	3	1
LARGE_INTESTINE	METTL21A →	+0.727	+3.064	.002	.009	3	1
LARGE_INTESTINE	SLC10A6 →	+0.438	+3.389	<.001	.007	3	1
LARGE_INTESTINE	ADAMTS19 →	+0.573	+3.302	.008	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

TFDP3 by SLC43A2 expression — LARGE_INTESTINE

Explore this box plot interactively →