SLC43A1

Across TCGA patient cohorts, SLC43A1 mutation is significantly associated with the total protein of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC43A1-associated genes across cancer lineages are eEF2, eIF4E, and A-Raf_pS299. Each is linked with SLC43A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC43A1-to-partner and partner-to-SLC43A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by SLC43A1-low versus SLC43A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC43A1→partner) and Y-score (partner→SLC43A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.387	+1.906	.007	.016	3	2
UCEC	eIF4E →	+0.183	+1.906	.031	.016	3	2
UCEC	A-Raf_pS299 →	-0.202	-3.584	<.001	.002	3	2
UCEC	PCNA →	+0.266	+2.906	.002	.001	3	2
UCEC	14-3-3_beta →	-0.107	-3.143	.008	.018	3	1
UCEC	ERK2 →	+0.174	+2.321	.025	.033	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

eEF2 by SLC43A1 expression — UCEC

Explore this box plot interactively →