SLC43A1

Across TCGA cell cohorts, SLC43A1 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible SLC43A1-associated genes across cancer lineages are NEXMIF, CST8, and KRTAP1-1. Each is linked with SLC43A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC43A1-to-partner and partner-to-SLC43A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NEXMIF grouped by SLC43A1-low versus SLC43A1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC43A1→partner) and Y-score (partner→SLC43A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	NEXMIF →	+0.175	+2.518	<.001	.006	3	1
OVARY	CST8 →	+0.012	+4.807	<.001	.003	3	1
OVARY	KRTAP1-1 →	+0.090	+4.450	<.001	.004	3	1
LARGE_INTESTINE	MTHFS →	+0.562	+3.215	.005	.009	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

NEXMIF by SLC43A1 expression — LARGE_INTESTINE

Explore this box plot interactively →