SLC41A3

Across TCGA patient cohorts, SLC41A3 mutation is significantly associated with the RNA expression of many other genes, with 3,758 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC41A3-associated genes across cancer lineages are DNM1P50, MIR6803, and RNA5SP273. Each is linked with SLC41A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC41A3-to-partner and partner-to-SLC41A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNM1P50 grouped by SLC41A3-low versus SLC41A3-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC41A3→partner) and Y-score (partner→SLC41A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DNM1P50 →	+0.074	+8.055	<.001	.007	3	2
COAD	MIR6803 →	+0.289	+4.136	<.001	.008	3	2
LUAD	RNA5SP273 →	+0.297	+6.739	<.001	<.001	3	2
LUAD	RNU6-129P →	+0.528	+6.315	<.001	.001	3	2
LUAD	HPRT1P3 →	+0.067	+6.444	<.001	.001	3	2
LUSC	RNA5SP420 →	+0.391	+4.724	.009	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,758 associations by consensus.

DNM1P50 by SLC41A3 expression — BRCA

Explore this box plot interactively →