SLC41A3

Across TCGA cell cohorts, SLC41A3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,149 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC41A3-associated GO terms across cancer lineages are Negative regulation of protein-containing complex assembly, Negative regulation of cytoskeleton organization, and Regulation of protein localization to nucleus. Each is linked with SLC41A3 in more than 8 cancer types. Because this analysis shows association rather than direction, both SLC41A3-to-partner and partner-to-SLC41A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein-containing complex assembly grouped by SLC41A3-low versus SLC41A3-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC41A3→partner) and Y-score (partner→SLC41A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of protein-containing complex assembly →	+0.102	+1.326	<.001	<.001	3	8
STOMACH	Negative regulation of cytoskeleton organization →	+0.065	+1.140	.002	.002	2	9
BONE	Regulation of protein localization to nucleus →	+0.071	+0.633	<.001	.004	3	8
BLOOD_Myeloma	Multivesicular body assembly →	+0.061	+1.106	.004	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Positive regulation of microtubule polymerization →	+0.066	+0.771	.001	<.001	3	7
LARGE_INTESTINE	Positive regulation of protein localization to nucleus →	+0.083	+0.674	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,149 associations by consensus.

Negative regulation of protein-containing complex assembly by SLC41A3 expression — STOMACH

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