SLC41A2

Across TCGA pan-cancer cohorts, SLC41A2 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated SLC41A2 data layer compared with 20 for mass-spec protein.

The strongest signal is observed in small cell lung cancer (SCLC), where higher SLC41A2 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated SLC41A2 expression acts as an unfavorable survival marker.

SCLC and LUAD are the cancer types where SLC41A2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	DFS	Median	All	0.096	0.633	<.001	24	view →
LUAD	OS	Median	All	0.211	0.837	<.001	15	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

SLC41A2–SCLC (DFS)

Open the SCLC breakdown →