SLC41A2

Across TCGA patient cohorts, SLC41A2 mutation is significantly associated with the RNA expression of many other genes, with 1,790 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC41A2-associated genes across cancer lineages are RSAD1, PGGT1BP2, and LINC00380. Each is linked with SLC41A2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC41A2-to-partner and partner-to-SLC41A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RSAD1 grouped by SLC41A2-low versus SLC41A2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC41A2→partner) and Y-score (partner→SLC41A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RSAD1 →	+0.387	+2.711	.001	.003	3	3
BLCA	PGGT1BP2 →	+0.221	+3.124	<.001	.004	3	2
BLCA	LINC00380 →	+0.162	+5.048	<.001	.002	3	2
UCEC	CWC25 →	+0.457	+4.053	<.001	<.001	3	2
UCEC	ZNHIT3 →	+0.425	+2.021	.001	.001	3	2
UCEC	ZNF280B →	+0.608	+2.403	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,790 associations by consensus.

RSAD1 by SLC41A2 expression — UCEC

Explore this box plot interactively →