SLC41A1

Across TCGA pan-cancer cohorts, SLC41A1 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SLC41A1 data layer compared with 24 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher SLC41A1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SLC41A1 expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

BRCA, SKCM, and STAD are the cancer types where SLC41A1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.107	0.578	.013	12	view →
SKCM	DFS	Median	II,III,IV	1.000	0.556	.006	11	view →
STAD	OS	Median	III,IV	0.184	0.641	.011	9	view →
SCLC	DFS	Median	All	0.192	0.793	.017	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SLC41A1–BRCA (OS)

Open the BRCA breakdown →