SLC41A1

Across TCGA patient cohorts, SLC41A1 mutation is significantly associated with the RNA expression of many other genes, with 2,327 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC41A1-associated genes across cancer lineages are VN1R91P, TSEN2P1, and RNU6-1112P. Each is linked with SLC41A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC41A1-to-partner and partner-to-SLC41A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VN1R91P grouped by SLC41A1-low versus SLC41A1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC41A1→partner) and Y-score (partner→SLC41A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	VN1R91P →	+0.199	+4.562	<.001	.006	3	3
SKCM	TSEN2P1 →	+0.017	+3.009	<.001	.009	3	3
SKCM	RNU6-1112P →	+0.247	+4.080	<.001	<.001	3	3
CESC	DAOA →	+0.036	+4.760	<.001	.003	3	3
UCEC	SLC25A17 →	+0.450	+3.098	<.001	<.001	3	2
UCEC	CINP →	+0.403	+3.732	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,327 associations by consensus.

VN1R91P by SLC41A1 expression — BLCA

Explore this box plot interactively →