SLC41A1

Across TCGA cell cohorts, SLC41A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,442 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC41A1-associated GO terms across cancer lineages are Regulation of hippo signaling, Negative regulation of hippo signaling, and Intracellular magnesium ion homeostasis. Each is linked with SLC41A1 in more than 16 cancer types. Because this analysis shows association rather than direction, both SLC41A1-to-partner and partner-to-SLC41A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of hippo signaling grouped by SLC41A1-low versus SLC41A1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC41A1→partner) and Y-score (partner→SLC41A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of hippo signaling →	+0.129	+0.995	<.001	<.001	3	17
SOFT_TISSUE	Negative regulation of hippo signaling →	+0.103	+1.204	<.001	<.001	3	16
BLOOD_Myeloma	Intracellular magnesium ion homeostasis →	+0.157	+1.296	<.001	<.001	2	16
BONE	Regulation of focal adhesion assembly →	+0.169	+0.707	<.001	.001	3	14
BONE	Positive regulation of focal adhesion assembly →	+0.207	+0.705	<.001	.001	3	14
BONE	Regulation of cell-substrate junction assembly →	+0.169	+0.707	<.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,442 associations by consensus.

Regulation of hippo signaling by SLC41A1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →