SLC41A1

Across TCGA cell cohorts, SLC41A1 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC41A1-associated genes across cancer lineages are APCS, HTR3D, and LYVE1. Each is linked with SLC41A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC41A1-to-partner and partner-to-SLC41A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, APCS grouped by SLC41A1-low versus SLC41A1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC41A1→partner) and Y-score (partner→SLC41A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	APCS →	+0.042	+4.523	.001	.004	3	1
BLOOD_Lymphoma	HTR3D →	+0.015	+5.247	<.001	.001	3	1
OVARY	LYVE1 →	+0.026	+4.029	.001	.009	3	1
SKIN	UCN3 →	+0.045	+4.977	<.001	.007	3	1
LARGE_INTESTINE	GJD2 →	+0.002	+3.700	<.001	.009	3	1
LARGE_INTESTINE	FANCD2OS →	+0.122	+3.362	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

APCS by SLC41A1 expression — BLOOD_Lymphoma

Explore this box plot interactively →