SLC40A1

Across TCGA cell cohorts, SLC40A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,629 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC40A1-associated GO terms across cancer lineages are Regulation of myoblast fusion, Copper ion export, and Detoxification of copper ion. Each is linked with SLC40A1 in more than 9 cancer types. Because this analysis shows association rather than direction, both SLC40A1-to-partner and partner-to-SLC40A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by SLC40A1-low versus SLC40A1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC40A1→partner) and Y-score (partner→SLC40A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of myoblast fusion →	+0.111	+2.142	<.001	<.001	3	10
URINARY_TRACT	Copper ion export →	-0.169	-2.246	<.001	.001	3	10
LARGE_INTESTINE	Detoxification of copper ion →	-0.285	-1.911	<.001	<.001	3	9
BREAST	Positive regulation of cell communication by electrical coupling →	+0.843	+1.759	<.001	.002	3	9
LARGE_INTESTINE	Stress response to copper ion →	-0.285	-1.911	<.001	<.001	3	9
OESOPHAGUS	ATP synthesis coupled electron transport →	+0.103	+1.837	.002	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,629 associations by consensus.

Regulation of myoblast fusion by SLC40A1 expression — OESOPHAGUS

Explore this box plot interactively →