SLC3A2

Across TCGA cell cohorts, SLC3A2 mutation is significantly associated with the RNA expression of many other genes, with 965 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC3A2-associated genes across cancer lineages are OR11H1, USP29, and OR11H2. Each is linked with SLC3A2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC3A2-to-partner and partner-to-SLC3A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR11H1 grouped by SLC3A2-low versus SLC3A2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC3A2→partner) and Y-score (partner→SLC3A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR11H1 →	+0.046	+5.643	<.001	.002	3	2
STOMACH	USP29 →	+0.024	+4.044	<.001	.003	3	2
LUNG_NSCLC_LUAD	OR11H2 →	+0.011	+4.481	.002	.001	3	2
BLOOD_Lymphoma	OR4M2 →	+0.031	+4.867	<.001	.009	3	2
URINARY_TRACT	SEL1L2 →	+0.030	+5.087	<.001	.004	3	1
OVARY	KRTAP5-6 →	+0.131	+3.700	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 965 associations by consensus.

OR11H1 by SLC3A2 expression — BLOOD_Lymphoma

Explore this box plot interactively →