SLC3A1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SLC3A1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,595 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SLC3A1-associated genes across cancer lineages are GGT1, LGALS2, and CCDC198. Each is linked with SLC3A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC3A1-to-partner and partner-to-SLC3A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC3A1 versus GGT1 in CCRCC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC3A1→partner) and Y-score (partner→SLC3A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCGGT1 →+0.440+0.321<.001<.00132
CCRCCLGALS2 →+0.988+0.377<.001<.00132
CCRCCCCDC198 →+1.018+0.519.002<.00132
CCRCCHPN →+1.408+0.658<.001<.00132
PDACPBLD →+0.834+1.171<.001<.00132
PDACREG1A →+3.501+0.940<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,595 associations by consensus.

SLC3A1 vs GGT1 — CCRCC

Per-sample scatter of SLC3A1 vs GGT1 in CCRCC (Pearson r = 0.47).

Explore this scatter interactively →

Exploration