SLC3A1

Across TCGA cell cohorts, SLC3A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,250 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC3A1-associated GO terms across cancer lineages are Cellular response to rapamycin, Negative regulation of CD8-positive, alpha-beta T cell differentiation, and Response to rapamycin. Each is linked with SLC3A1 in more than 6 cancer types. Because this analysis shows association rather than direction, both SLC3A1-to-partner and partner-to-SLC3A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to rapamycin grouped by SLC3A1-low versus SLC3A1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC3A1→partner) and Y-score (partner→SLC3A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Cellular response to rapamycin →	-0.126	-1.928	<.001	<.001	3	7
STOMACH	Negative regulation of CD8-positive, alpha-beta T cell differentiation →	+0.224	+2.968	<.001	.002	3	6
LARGE_INTESTINE	Response to rapamycin →	-0.127	-1.634	<.001	<.001	3	6
OVARY	Regulation of vascular permeability involved in acute inflammatory response →	-0.434	-1.905	.003	<.001	3	6
UPPER_AERODIGESTIVE_TRACT	Surfactant homeostasis →	+0.234	+0.060	.001	.001	3	5
KIDNEY	Cellular response to ether →	-0.185	-2.456	.001	<.001	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,250 associations by consensus.

Cellular response to rapamycin by SLC3A1 expression — OVARY

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