SLC3A1

Across TCGA cell cohorts, SLC3A1 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SLC3A1-associated genes across cancer lineages are INSL5, SPZ1, and TGIF2LY. Each is linked with SLC3A1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC3A1-to-partner and partner-to-SLC3A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INSL5 grouped by SLC3A1-low versus SLC3A1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC3A1→partner) and Y-score (partner→SLC3A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	INSL5 →	+0.087	+3.980	<.001	.002	3	2
OESOPHAGUS	SPZ1 →	+0.530	+4.906	<.001	.006	3	1
BREAST	TGIF2LY →	+0.022	+5.169	<.001	.005	3	1
BREAST	IFNA2 →	+0.032	+5.169	<.001	.005	3	1
SKIN	C7orf77 →	+0.089	+5.415	<.001	.004	3	1
BLOOD_Leukemia	SCGB1D2 →	+0.090	+3.177	.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

INSL5 by SLC3A1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →