SLC39A9

Across TCGA pan-cancer cohorts, SLC39A9 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SLC39A9 data layer compared with 24 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher SLC39A9 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated SLC39A9 expression acts as an unfavorable survival marker, although some lineages such as PDAC and HNSC show a favorable association.

PDAC, HNSC, and CCRCC are the cancer types where SLC39A9 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Tertile	All	0.741	0.354	.001	35	view →
HNSC	DFS	Quartile	III,IV	0.915	0.430	.001	25	view →
CCRCC	OS	Tertile	IV	0.174	0.961	.036	3	view →
GBM	OS	Quartile	All	1.000	0.838	.034	1	view →
LUAD	DFS	Tertile	All	0.907	0.411	.019	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

SLC39A9–PDAC (OS)

Open the PDAC breakdown →