SLC39A9

Across TCGA pan-cancer cohorts, SLC39A9 mass-spec protein differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of SLC39A9’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where SLC39A9 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types SLC39A9 is over-expressed in tumor, although a few such as PDAC and CCRCC show the opposite, repressed pattern.

LUAD, PDAC, and CCRCC are the cancer types where SLC39A9 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SLC39A9 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	II,III,IV	+0.626	<.001	8	view →
PDAC	All	All	−0.756	<.001	6	view →
CCRCC	All	All	−0.226	<.001	6	view →
LSCC	Male	All	+0.487	<.001	5	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

SLC39A9–LUAD

Open the LUAD breakdown →