SLC39A9

Across TCGA patient cohorts, SLC39A9 mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC39A9-associated genes across cancer lineages are 14-3-3_beta, ACC_pS79, and ACC1. Each is linked with SLC39A9 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC39A9-to-partner and partner-to-SLC39A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 14-3-3_beta grouped by SLC39A9-low versus SLC39A9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A9→partner) and Y-score (partner→SLC39A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.089	-2.295	.023	.033	3	1
UCEC	ACC_pS79 →	+0.304	+2.009	.025	.017	3	1
UCEC	ACC1 →	+0.386	+2.000	.006	.010	3	1
UCEC	JNK2 →	+0.195	+2.196	.012	.032	3	1
UCEC	p62 Lck ligand →	+0.447	+2.594	<.001	.006	3	1
UCEC	PDCD4 →	-0.494	-2.459	.007	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

14-3-3_beta by SLC39A9 expression — UCEC

Explore this box plot interactively →