SLC39A9

Across TCGA cell cohorts, SLC39A9 mutation is significantly associated with the mutation status of many other genes, with 1,948 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC39A9-associated genes across cancer lineages are ACVR2B, SEC14L4, and ZMYND15. Each is linked with SLC39A9 in more than 2 cancer types. Because this analysis shows association rather than direction, both SLC39A9-to-partner and partner-to-SLC39A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACVR2B grouped by SLC39A9-low versus SLC39A9-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A9→partner) and Y-score (partner→SLC39A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	ACVR2B →	+5.824	+5.824	.002	.002	1	3
SKIN	SEC14L4 →	+5.824	+5.824	.002	.002	1	3
SKIN	ZMYND15 →	+4.824	+5.392	.004	.004	1	3
SKIN	FCRL4 →	+4.239	+5.053	.007	.007	1	3
SKIN	JMJD7-PLA2G4B →	+4.824	+5.392	.004	.004	1	3
LARGE_INTESTINE	CLCN5 →	+5.087	+4.523	.006	.006	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,948 associations by consensus.

ACVR2B by SLC39A9 expression — SKIN

Explore this box plot interactively →