SLC39A6

Across TCGA patient cohorts, SLC39A6 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,018 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SLC39A6-associated proteins across cancer lineages are SMAD4, TXNL1, and RPRD1A. Each is linked with SLC39A6 in more than 6 cancer types. Because this analysis shows association rather than direction, both SLC39A6-to-partner and partner-to-SLC39A6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC39A6 versus SMAD4 in PDAC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A6→partner) and Y-score (partner→SLC39A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SMAD4 →	+0.290	+0.502	<.001	<.001	3	7
COAD	TXNL1 →	+0.369	+0.463	.002	.003	3	6
OV	RPRD1A →	+0.385	+0.592	.002	.001	3	6
GBM	ZNF24 →	+0.426	+0.560	<.001	<.001	3	5
UCEC	CAPG →	-0.468	-0.604	<.001	<.001	3	5
GBM	CASP1 →	-0.506	-0.617	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,018 associations by consensus.

SLC39A6 vs SMAD4 — PDAC

Explore this scatter interactively →