SLC39A6

Across TCGA patient cohorts, SLC39A6 mutation is significantly associated with the RNA expression of many other genes, with 2,349 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC39A6-associated genes across cancer lineages are AMZ2P3, ZMYND19, and RNU6-993P. Each is linked with SLC39A6 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC39A6-to-partner and partner-to-SLC39A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AMZ2P3 grouped by SLC39A6-low versus SLC39A6-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A6→partner) and Y-score (partner→SLC39A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	AMZ2P3 →	+0.027	+4.039	.003	.009	3	4
UCEC	ZMYND19 →	+0.512	+2.032	<.001	<.001	3	3
BLCA	RNU6-993P →	+0.313	+5.147	<.001	.003	3	2
BLCA	ZFP64P1 →	+0.062	+4.208	<.001	.009	3	2
UCEC	CTU2 →	+0.735	+2.711	<.001	<.001	3	2
UCEC	SSNA1 →	+0.324	+2.593	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,349 associations by consensus.

AMZ2P3 by SLC39A6 expression — SKCM

Explore this box plot interactively →