SLC39A6

Across TCGA cell cohorts, SLC39A6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,991 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC39A6-associated GO terms across cancer lineages are Midbody abscission, Regulation of microtubule polymerization or depolymerization, and Nuclear membrane reassembly. Each is linked with SLC39A6 in more than 10 cancer types. Because this analysis shows association rather than direction, both SLC39A6-to-partner and partner-to-SLC39A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Midbody abscission grouped by SLC39A6-low versus SLC39A6-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A6→partner) and Y-score (partner→SLC39A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Midbody abscission →	+0.079	+0.713	<.001	.001	3	11
LUNG_SCLC	Regulation of microtubule polymerization or depolymerization →	+0.098	+0.634	<.001	.004	3	10
OVARY	Nuclear membrane reassembly →	+0.095	+0.909	<.001	<.001	3	9
LIVER	Cytoskeleton-dependent cytokinesis →	+0.101	+1.659	<.001	<.001	3	9
LARGE_INTESTINE	Viral budding from plasma membrane →	+0.106	+1.034	<.001	.001	3	9
LARGE_INTESTINE	ESCRT complex disassembly →	+0.103	+0.977	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,991 associations by consensus.

Midbody abscission by SLC39A6 expression — LUNG_SCLC

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