SLC39A5

Across TCGA cell cohorts, SLC39A5 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. CNS shows the largest number of these associations.

The most reproducible SLC39A5-associated genes across cancer lineages are CEACAM3, DEFB4A, and PRR30. Each is linked with SLC39A5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC39A5-to-partner and partner-to-SLC39A5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CEACAM3 grouped by SLC39A5-low versus SLC39A5-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A5→partner) and Y-score (partner→SLC39A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	CEACAM3 →	+0.035	+4.321	<.001	.009	3	1
CNS	DEFB4A →	+0.169	+5.357	<.001	.001	3	1
CNS	PRR30 →	+0.015	+4.643	<.001	.003	3	1
CNS	FABP12 →	+0.213	+5.566	<.001	<.001	3	1
CNS	OR2B3 →	+0.029	+4.321	<.001	.009	3	1
CNS	KRTAP19-3 →	+0.068	+4.321	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

CEACAM3 by SLC39A5 expression — CNS

Explore this box plot interactively →