SLC39A4

Across TCGA patient cohorts, SLC39A4 protein abundance is significantly associated with the RNA expression of many other genes, with 1,709 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SLC39A4-associated genes across cancer lineages are ACVR1B, WDR43, and PPP1R14D. Each is linked with SLC39A4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC39A4-to-partner and partner-to-SLC39A4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SLC39A4 versus ACVR1B in LUAD, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A4→partner) and Y-score (partner→SLC39A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ACVR1B →	+0.623	+0.758	.001	.009	3	2
LUAD	WDR43 →	+0.376	+0.851	.006	.002	3	2
LUAD	PPP1R14D →	+1.930	+1.074	<.001	<.001	3	2
LUAD	RNU6-1208P →	-1.033	-1.048	<.001	<.001	3	2
COAD	IFT27 →	-0.543	-1.242	.001	.008	3	2
COAD	TNFAIP8 →	-0.701	-1.223	.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,709 associations by consensus.

SLC39A4 vs ACVR1B — LUAD

Explore this scatter interactively →