SLC39A4

Across TCGA patient cohorts, SLC39A4 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC39A4-associated genes across cancer lineages are ERK2 and AR. Each is linked with SLC39A4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC39A4-to-partner and partner-to-SLC39A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERK2 grouped by SLC39A4-low versus SLC39A4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A4→partner) and Y-score (partner→SLC39A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.219	+2.321	.023	.035	3	1
UCEC	AR →	-0.375	-2.321	.045	.035	2	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

ERK2 by SLC39A4 expression — UCEC

Explore this box plot interactively →