SLC39A4

Across TCGA cell cohorts, SLC39A4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,768 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SLC39A4-associated GO terms across cancer lineages are Cellular response to salt, Response to sodium arsenite, and Cellular response to sodium arsenite. Each is linked with SLC39A4 in more than 8 cancer types. Because this analysis shows association rather than direction, both SLC39A4-to-partner and partner-to-SLC39A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to salt grouped by SLC39A4-low versus SLC39A4-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A4→partner) and Y-score (partner→SLC39A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Cellular response to salt →	+0.124	+1.685	<.001	<.001	3	9
BONE	Response to sodium arsenite →	+0.150	+1.695	<.001	<.001	3	8
BONE	Cellular response to sodium arsenite →	+0.134	+1.561	<.001	.002	2	9
PANCREAS	Protein localization to synapse →	+0.098	+1.286	<.001	<.001	3	8
OESOPHAGUS	U4 snRNA 3'-end processing →	+0.143	+1.328	.002	.004	3	7
UPPER_AERODIGESTIVE_TRACT	Enzyme-directed rRNA pseudouridine synthesis →	+0.084	+1.062	.003	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,768 associations by consensus.

Cellular response to salt by SLC39A4 expression — BLOOD_Leukemia

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