SLC39A3

Across TCGA patient cohorts, SLC39A3 RNA expression is significantly associated with the mutation status of many other genes, with 8,973 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC39A3-associated genes across cancer lineages are FAM135B, CSMD1, and LYST. Each is linked with SLC39A3 in more than 3 cancer types. Because this analysis shows association rather than direction, both SLC39A3-to-partner and partner-to-SLC39A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM135B grouped by SLC39A3-low versus SLC39A3-high in UCEC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A3→partner) and Y-score (partner→SLC39A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FAM135B →	+1.497	+0.393	<.001	<.001	3	4
LUSC	CSMD1 →	+1.087	+0.230	.008	<.001	3	4
STAD	LYST →	+2.148	+0.296	.008	.004	3	4
GBM	MUC16 →	+3.000	+0.322	<.001	.005	3	4
UCEC	FCGBP →	+1.338	+0.258	<.001	.003	3	4
UCEC	LRP2 →	+1.079	+0.335	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,973 associations by consensus.

FAM135B by SLC39A3 expression — UCEC

Explore this box plot interactively →