SLC39A3

Across TCGA cell cohorts, SLC39A3 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SLC39A3-associated genes across cancer lineages are CRYGC and SPEM3. Each is linked with SLC39A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC39A3-to-partner and partner-to-SLC39A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CRYGC grouped by SLC39A3-low versus SLC39A3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A3→partner) and Y-score (partner→SLC39A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CRYGC →	+0.026	+4.969	<.001	.003	3	1
BLOOD_Leukemia	SPEM3 →	+0.013	+4.409	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CRYGC by SLC39A3 expression — BLOOD_Leukemia

Explore this box plot interactively →