SLC39A14

Across TCGA patient cohorts, SLC39A14 mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SLC39A14-associated genes across cancer lineages are MEK1, Annexin-1, and ATM. Each is linked with SLC39A14 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC39A14-to-partner and partner-to-SLC39A14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEK1 grouped by SLC39A14-low versus SLC39A14-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A14→partner) and Y-score (partner→SLC39A14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.409	+3.087	.005	<.001	3	2
UCEC	Annexin-1 →	+0.680	+2.604	.001	.005	3	2
UCEC	ATM →	-0.396	-3.308	.030	.009	3	2
UCEC	EGFR_pY1068 →	-0.226	-1.906	.025	.016	3	1
UCEC	JNK2 →	+0.157	+2.415	.049	.003	3	1
UCEC	p21 →	+0.166	+2.183	.031	.033	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

MEK1 by SLC39A14 expression — UCEC

Explore this box plot interactively →