SLC39A14

Across TCGA cell cohorts, SLC39A14 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,258 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SLC39A14-associated GO terms across cancer lineages are IMP biosynthetic process, Manganese ion transmembrane transport, and Iron import into cell. Each is linked with SLC39A14 in more than 10 cancer types. Because this analysis shows association rather than direction, both SLC39A14-to-partner and partner-to-SLC39A14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IMP biosynthetic process grouped by SLC39A14-low versus SLC39A14-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A14→partner) and Y-score (partner→SLC39A14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	IMP biosynthetic process →	+0.165	+1.195	.006	.002	3	11
BREAST	Manganese ion transmembrane transport →	+0.155	+1.428	.001	.002	3	11
BREAST	Iron import into cell →	+0.237	+1.368	<.001	<.001	3	10
PANCREAS	Manganese ion homeostasis →	+0.190	+1.111	<.001	.002	3	10
BLOOD_Lymphoma	Multi-pass transmembrane protein insertion into ER membrane →	+0.128	+1.208	<.001	<.001	3	10
BREAST	Positive regulation of DNA damage checkpoint →	+0.094	+1.204	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,258 associations by consensus.

IMP biosynthetic process by SLC39A14 expression — URINARY_TRACT

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