SLC39A14

Across TCGA cell cohorts, SLC39A14 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SLC39A14-associated genes across cancer lineages are GABRA6, GPHB5, and MAGEB4. Each is linked with SLC39A14 in more than 1 cancer types. Because this analysis shows association rather than direction, both SLC39A14-to-partner and partner-to-SLC39A14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GABRA6 grouped by SLC39A14-low versus SLC39A14-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A14→partner) and Y-score (partner→SLC39A14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	GABRA6 →	+0.159	+4.684	<.001	.002	3	2
LUNG_NSCLC_LUAD	GPHB5 →	+0.036	+4.887	.004	.009	3	2
LARGE_INTESTINE	MAGEB4 →	+0.012	+3.678	<.001	.001	3	1
LARGE_INTESTINE	C3orf20 →	+0.091	+3.464	<.001	.004	3	1
LARGE_INTESTINE	OR4F4 →	+0.012	+2.688	.001	.008	3	1
LARGE_INTESTINE	ODF3 →	+0.033	+3.836	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

GABRA6 by SLC39A14 expression — SKIN

Explore this box plot interactively →