SLC39A12

Across TCGA patient cohorts, SLC39A12 mutation is significantly associated with the RNA expression of many other genes, with 4,161 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SLC39A12-associated genes across cancer lineages are CFI, HROB, and TUBG1. Each is linked with SLC39A12 in more than 4 cancer types. Because this analysis shows association rather than direction, both SLC39A12-to-partner and partner-to-SLC39A12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CFI grouped by SLC39A12-low versus SLC39A12-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SLC39A12→partner) and Y-score (partner→SLC39A12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CFI →	-1.408	-3.881	<.001	<.001	3	5
LUAD	HROB →	+0.711	+2.497	<.001	<.001	3	4
BLCA	TUBG1 →	+0.603	+3.329	.003	.005	3	4
SKCM	POC1A →	+0.510	+2.273	<.001	.004	3	4
UCEC	AOC2 →	+0.919	+2.078	<.001	<.001	3	4
HNSC	ZNF468 →	+0.797	+2.807	.002	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,161 associations by consensus.

CFI by SLC39A12 expression — SKCM

Explore this box plot interactively →